Mouse Anti-TRAT1 Recombinant Antibody (TRIM-04) (CBMAB-T4087-YJ)

Name: Mouse Anti-TRAT1 Recombinant Antibody (TRIM-04)
SKU: CBMAB-T4087-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

TRIM-04

Application

WB, FC, IP, CyTOF

Immunogen

Recombinant fragment, corresponding to amino acids 29-186 of Human TRIM

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 29-186

More Infomation

Target

Full Name

T Cell Receptor Associated Transmembrane Adaptor 1

Introduction

TRAT1 (T Cell Receptor Associated Transmembrane Adaptor 1) is a Protein Coding gene. Among its related pathways are RET signaling and Innate Immune System. Gene Ontology (GO) annotations related to TRAT1 include transmembrane receptor protein tyrosine kinase adaptor activity.

Entrez Gene ID

50852

UniProt ID

Q6PIZ9

Alternative Names

T Cell Receptor Associated Transmembrane Adaptor 1; TCRIM; Pp29/30; TRIM; T-Cell Receptor-Associated Transmembrane Adapter 1; T-Cell Receptor Associated Transmembrane Adaptor 1; T Cell Receptor Interacting Molecule; T-Cell Receptor-Interacting Molecule; HSPC062

Function

Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.

Biological Process

Biological Process adaptive immune response Source:UniProtKB-KW
Biological Process cellular defense response Source:ProtInc1 Publication
Biological Process negative regulation of receptor recycling Source:MGI1 Publication
Biological Process negative regulation of transport Source:MGI1 Publication
Biological Process positive regulation of calcium-mediated signaling Source:MGI1 Publication
Biological Process positive regulation of T cell receptor signaling pathway Source:MGI1 Publication
Biological Process signal transduction Source:ProtInc1 Publication

Cellular Location

Cell membrane

Topology

Extracellular: 1-7
Helical: 8-28
Cytoplasmic: 29-186

PTM

Phosphorylated on tyrosines by LCK or FYN upon TCR activation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Mouse Anti-TRAT1 Recombinant Antibody (CBYJT-4573) (CAT#: CBMAB-T4086-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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