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TRAT1

TRAT1 (T Cell Receptor Associated Transmembrane Adaptor 1) is a Protein Coding gene. Among its related pathways are RET signaling and Innate Immune System. Gene Ontology (GO) annotations related to TRAT1 include transmembrane receptor protein tyrosine kinase adaptor activity.
Full Name
T Cell Receptor Associated Transmembrane Adaptor 1
Function
Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
Biological Process
Biological Process adaptive immune response Source:UniProtKB-KW
Biological Process cellular defense response Source:ProtInc1 Publication
Biological Process negative regulation of receptor recycling Source:MGI1 Publication
Biological Process negative regulation of transport Source:MGI1 Publication
Biological Process positive regulation of calcium-mediated signaling Source:MGI1 Publication
Biological Process positive regulation of T cell receptor signaling pathway Source:MGI1 Publication
Biological Process signal transduction Source:ProtInc1 Publication
Cellular Location
Cell membrane
Topology
Extracellular: 1-7
Helical: 8-28
Cytoplasmic: 29-186
PTM
Phosphorylated on tyrosines by LCK or FYN upon TCR activation.
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Anti-TRAT1 antibodies

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Mouse Anti-TRAT1 Recombinant Antibody (CBYJT-4572) (CBMAB-T4085-YJ)

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Target: TRAT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4572
Application*: WB, IS
Datasheet SDS

Mouse Anti-TRAT1 Recombinant Antibody (TRIM-04) (CBMAB-T4087-YJ)

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Target: TRAT1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: TRIM-04
Application*: WB, F, IP, MC
Datasheet SDS

Mouse Anti-TRAT1 Recombinant Antibody (CBYJT-4573) (CBMAB-T4086-YJ)

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Target: TRAT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4573
Application*: F, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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