TRAT1

TRAT1 (T Cell Receptor Associated Transmembrane Adaptor 1) is a Protein Coding gene. Among its related pathways are RET signaling and Innate Immune System. Gene Ontology (GO) annotations related to TRAT1 include transmembrane receptor protein tyrosine kinase adaptor activity.

T Cell Receptor Associated Transmembrane Adaptor 1

Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.

Biological Process adaptive immune response Source:UniProtKB-KW
Biological Process cellular defense response Source:ProtInc1 Publication
Biological Process negative regulation of receptor recycling Source:MGI1 Publication
Biological Process negative regulation of transport Source:MGI1 Publication
Biological Process positive regulation of calcium-mediated signaling Source:MGI1 Publication
Biological Process positive regulation of T cell receptor signaling pathway Source:MGI1 Publication
Biological Process signal transduction Source:ProtInc1 Publication

Cell membrane

Extracellular: 1-7
Helical: 8-28
Cytoplasmic: 29-186

Phosphorylated on tyrosines by LCK or FYN upon TCR activation.