Mouse Anti-TRIM46 Recombinant Antibody (CBYJT-4793) (CBMAB-T4334-YJ)

Name: Mouse Anti-TRIM46 Recombinant Antibody (CBYJT-4793)
SKU: CBMAB-T4334-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYJT-4793

Application

ELISA, ICC, IF

Immunogen

TRIM46 (NP_079334, 451 a.a. ~ 560 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 451-560

More Infomation

Target

Full Name

tripartite motif-containing 46

Introduction

TRIM46 (Tripartite Motif Containing 46) is a Protein Coding gene. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. An important paralog of TRIM46 is TRIM36.

Entrez Gene ID

80128

UniProt ID

Q7Z4K8

Alternative Names

Tripartite Motif Containing 46; Tripartite, Fibronectin Type-III And C-Terminal SPRY Motif Protein; Gene Y Protein; TRIFIC; GENEY; Tripartite Motif-Containing Protein 46; Tripartite Motif-Containing 46

Function

Microtubule-associated protein that is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for the uniform orientation and maintenance of the parallel microtubule fascicles, which are important for efficient cargo delivery and trafficking in axons. Thereby also required for proper axon specification, the establishment of neuronal polarity and proper neuronal migration.

Biological Process

Biological Process anterograde synaptic vesicle transport Source:GO_Central1 Publication
Biological Process axonogenesis Source:GO_Central1 Publication
Biological Process microtubule bundle formation Source:GO_Central1 Publication
Biological Process negative regulation of axon extension Source:ARUK-UCL
Biological Process neuron migration Source:GO_Central1 Publication
Biological Process positive regulation of anterograde dense core granule transport Source:ARUK-UCL
Biological Process protein localization to axon Source:Ensembl
Biological Process regulation of protein localization Source:ARUK-UCL

Cellular Location

Cell projection, axon
Cytoplasm, cytoskeleton
Microtubule-associated. Localizes to the proximal part of the axon.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-TRIM46 Recombinant Antibody (CBYJT-4794) (CAT#: CBMAB-T4335-YJ)

Mouse Anti-TRIM46 Recombinant Antibody (3G11) (CAT#: CBMAB-A9520-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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