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Mouse Anti-TRIM46 Recombinant Antibody (CBYJT-4793) (CBMAB-T4334-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TRIM46 (Tripartite Motif Containing 46). The antibody can be used for immunoassay techniques, such as ELISA, ICC, IF.
See all TRIM46 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-4793
Antibody Isotype
IgG2a, κ
Application
ELISA, ICC, IF

Basic Information

Immunogen
TRIM46 (NP_079334, 451 a.a. ~ 560 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 451-560

Target

Full Name
tripartite motif-containing 46
Introduction
TRIM46 (Tripartite Motif Containing 46) is a Protein Coding gene. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. An important paralog of TRIM46 is TRIM36.
Entrez Gene ID
80128
UniProt ID
Q7Z4K8
Alternative Names
Tripartite Motif Containing 46; Tripartite, Fibronectin Type-III And C-Terminal SPRY Motif Protein; Gene Y Protein; TRIFIC; GENEY; Tripartite Motif-Containing Protein 46; Tripartite Motif-Containing 46
Function
Microtubule-associated protein that is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for the uniform orientation and maintenance of the parallel microtubule fascicles, which are important for efficient cargo delivery and trafficking in axons. Thereby also required for proper axon specification, the establishment of neuronal polarity and proper neuronal migration.
Biological Process
Biological Process anterograde synaptic vesicle transport Source:GO_Central1 Publication
Biological Process axonogenesis Source:GO_Central1 Publication
Biological Process microtubule bundle formation Source:GO_Central1 Publication
Biological Process negative regulation of axon extension Source:ARUK-UCL
Biological Process neuron migration Source:GO_Central1 Publication
Biological Process positive regulation of anterograde dense core granule transport Source:ARUK-UCL
Biological Process protein localization to axon Source:Ensembl
Biological Process regulation of protein localization Source:ARUK-UCL
Cellular Location
Cell projection, axon
Cytoplasm, cytoskeleton
Microtubule-associated. Localizes to the proximal part of the axon.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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