Sign in or Register   Sign in or Register
  |  

Mouse Anti-TRIM62 Recombinant Antibody (4A4) (CBMAB-A9533-LY)

The product is antibody recognizes TRIM62. The antibody 4A4 immunoassay techniques such as: sELISA, ELISA.
See all TRIM62 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4A4
Antibody Isotype
IgG2a, κ
Application
sELISA, ELISA

Basic Information

Immunogen
TRIM62 (NP_060677, 376 a.a. ~ 475 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
tripartite motif-containing 62
Entrez Gene ID
55223
UniProt ID
Q9BVG3
Alternative Names
FLJ10759; FLJ16558
Function
E3 ubiquitin ligase that plays a role in antifungal immunity by mediating 'Lys-27'-linked ubiquitination of CARD9 downstream of C-type lectin receptors; leading to CARD9 activation, followed by activation of NF-kappa-B and MAP kinase p38 pathways (PubMed:26488816).
E3 ubiquitin ligase activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2 (PubMed:23402750).
Biological Process
Biological Process innate immune response Source:UniProtKB1 Publication
Biological Process negative regulation of epithelial to mesenchymal transition Source:Ensembl
Biological Process negative regulation of viral transcription Source:UniProtKB1 Publication
Biological Process positive regulation of antifungal innate immune response Source:UniProtKB1 Publication
Biological Process positive regulation of DNA-binding transcription factor activity Source:UniProtKB1 Publication
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signaling Source:UniProtKB1 Publication
Biological Process positive regulation of NF-kappaB transcription factor activity Source:UniProtKB1 Publication
Biological Process protein K27-linked ubiquitination Source:UniProtKB1 Publication
Biological Process protein ubiquitination Source:GO_Central1 Publication
Biological Process regulation of viral entry into host cell Source:UniProtKB1 Publication
Biological Process viral release from host cell Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
PTM
Polyubiquitinated, autoubiquitinated in the presence of UBE2D2.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-TRIM62 Recombinant Antibody (4A4)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare