Sign in or Register
  • Home
  • TRPC3
  • Rabbit Anti-TRPC3 Recombinant Antibody (D4P5S)

Rabbit Anti-TRPC3 Recombinant Antibody (D4P5S) (CBMAB-CP2878-LY)

See all TRPC3 antibodies
Go to compare Compare Online Inquiry
Datasheet
SDS
Request for COA
Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Rabbit
Clone
D4P5S
Application
WB, IP
Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human TRPC3 protein.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
TRPC3 Gene(Protein Coding) Transient Receptor Potential Cation Channel Subfamily C Member 3
Introduction
The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Entrez Gene ID
Human7222
Mouse22065
Rat60395
UniProt ID
HumanQ13507
MouseQ9QZC1
RatQ9JMI9
Alternative Names
Transient Receptor Potential Cation Channel Subfamily C Member 3; Transient Receptor Protein 3; HTrp-3; TRP3; Transient Receptor Potential Cation Channel Subfamily C Member 3 Variant C; Transient Receptor Potential Cation Channel; Subfamily C; Member 3;
Function
Forms a receptor-activated non-selective calcium permeant cation channel (PubMed:8646775, PubMed:9417057, PubMed:9930701, PubMed:20095964, PubMed:30139744, PubMed:29726814, PubMed:35051376).
May be operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors (PubMed:8646775).
Biological Process
Biological Process calcium ion transmembrane transport Source:UniProtKB1 Publication
Biological Process calcium ion transport Source:ProtInc1 Publication
Biological Process manganese ion transport Source:GO_Central1 Publication
Biological Process phototransduction Source:ProtInc1 Publication
Biological Process positive regulation of calcium ion transport into cytosol Source:UniProtKB1 Publication
Biological Process positive regulation of cardiac muscle hypertrophy in response to stress Source:BHF-UCL1 Publication
Biological Process regulation of cytosolic calcium ion concentration Source:GO_Central1 Publication
Biological Process response to ATP Source:UniProtKB1 Publication
Biological Process response to calcium ion Source:UniProtKB1 Publication
Biological Process single fertilization Source:GO_Central1 Publication
Cellular Location
Cell membrane
Involvement in disease
Spinocerebellar ataxia 41 (SCA41):
A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord.
Topology
Cytoplasmic: 1-459
Helical: 460-477
Extracellular: 478-508
Helical: 509-527
Cytoplasmic: 528-540
Helical: 541-562
Extracellular: 563-606
Helical: 607-630
Cytoplasmic: 631-649
Helical: 650-673
Extracellular: 674-713
Helical: 714-739
Cytoplasmic: 740-921
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-TRPC3 Recombinant Antibody (D4P5S)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-TRPC3 Recombinant Antibody (CBYJT-4899) (CAT#: CBMAB-T4445-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry
Request bulk or custom quote Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry