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Mouse Anti-TSGA10 Recombinant Antibody (CBYJT-5009) (CBMAB-T4566-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TSGA10 (Testis Specific 10). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all TSGA10 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-5009
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa599-699 from human TSGA10 (NP_079520) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 599-699

Target

Full Name
testis specific, 10
Introduction
TSGA10 (Testis Specific 10 Interacting Protein) is a Protein Coding gene. It functions in cell projection assembly, spermatogenesis.
Entrez Gene ID
80705
UniProt ID
Q9BZW7
Alternative Names
Testis Specific 10; Testis Development Protein NYD-SP7; Cancer/Testis Antigen 79; CEP4L; Testis-Specific Gene 10 Protein; Testis-Specific 10 Protein; CT79
Function
Plays a role in spermatogenesis (PubMed:28905369).
When overexpressed, prevents nuclear localization of HIF1A (By similarity).
Biological Process
Biological Process spermatogenesis Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
In mature spermatozoa, localizes to the centriole and midpiece (PubMed:28905369).
The 27-kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa peptide localizes to the midpiece (By similarity).
Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (By similarity).
Involvement in disease
Spermatogenic failure 26 (SPGF26):
An autosomal recessive infertility disorder caused by spermatogenesis defects that result in acephalic spermatozoa.
PTM
Processed into N-terminal 27-kDa and C-terminal 55-kDa fragments.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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