Mouse Anti-TSGA10 Recombinant Antibody (CBYJT-5009) (CBMAB-T4566-YJ)

Name: Mouse Anti-TSGA10 Recombinant Antibody (CBYJT-5009)
SKU: CBMAB-T4566-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYJT-5009

Application

ELISA, WB

Immunogen

Partial recombinant corresponding to aa599-699 from human TSGA10 (NP_079520) with GST tag. MW of the GST tag alone is 26kD

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.2

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 599-699

More Infomation

Target

Full Name

testis specific, 10

Introduction

TSGA10 (Testis Specific 10 Interacting Protein) is a Protein Coding gene. It functions in cell projection assembly, spermatogenesis.

Entrez Gene ID

80705

UniProt ID

Q9BZW7

Alternative Names

Testis Specific 10; Testis Development Protein NYD-SP7; Cancer/Testis Antigen 79; CEP4L; Testis-Specific Gene 10 Protein; Testis-Specific 10 Protein; CT79

Function

Plays a role in spermatogenesis (PubMed:28905369).
When overexpressed, prevents nuclear localization of HIF1A (By similarity).

Biological Process

Biological Process spermatogenesis Source:UniProtKB1 Publication

Cellular Location

Cytoplasm
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
In mature spermatozoa, localizes to the centriole and midpiece (PubMed:28905369).
The 27-kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa peptide localizes to the midpiece (By similarity).
Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (By similarity).

Involvement in disease

Spermatogenic failure 26 (SPGF26):
An autosomal recessive infertility disorder caused by spermatogenesis defects that result in acephalic spermatozoa.

PTM

Processed into N-terminal 27-kDa and C-terminal 55-kDa fragments.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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