Mouse Anti-TSKS Recombinant Antibody (CBYJT-5038) (CBMAB-T4613-YJ)

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Basic Information

Host Animal
Mouse
Clone
CBYJT-5038
Application
ELISA, WB
Immunogen
Partial recombinant corresponding to aa471-561 from human TSKS (NP_068379) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 471-561
More Infomation

Target

Full Name
testis-specific kinase substrate
Introduction
TSKS may function in testicular physiology, spermatogenesis or spermiogenesis. Expression of the encoded protein is highest in the testis and down-regulated in testicular cancer. TSKS is localized to the region 19q13.3 among the related RAS viral oncogene homolog (RRAS) and interferon regulatory factor 3 (IRF3) genes, which are both involved in tumorigenesis pathways and progression.
Entrez Gene ID
UniProt ID
Alternative Names
Testis Specific Serine Kinase Substrate; Protein Phosphatase 1, Regulatory Subunit 161; Testis-Specific Kinase Substrate; STK22 Substrate 1; STK22S1; TSKS1
Function
May play a role in testicular physiology, most probably in the process of spermatogenesis or spermatid development.
Cellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
Concentrates in spermatid centrioles during flagellogenesis.
PTM
Phosphorylated on serine residue(s) by STK22A/TSSK1 and STK22B/TSSK2.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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