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Mouse Anti-TSPAN2 Recombinant Antibody (CBYJT-5070) (CBMAB-T4648-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TSPAN2 (Tetraspanin 2). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all TSPAN2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-5070
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
TSPAN2 (NP_005716, 112 a.a. ~ 187 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: GKGVAIRHVQ TMYEEAYNDY LKDRGKGNGT LITFHSTFQC CGKESSEQVQ PTCPKELLGH KNCIDEIETI ISVKLQ
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 112-187

Target

Full Name
tetraspanin 2
Introduction
TSPAN2 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It mediate signal transduction events that function in the regulation of cell development, activation, growth and motility.
Entrez Gene ID
10100
UniProt ID
O60636
Alternative Names
Tetraspanin 2; Tetraspan NET-3; TSPAN-2; Tetraspanin 2 Isoform; New EST Tetraspan 3; Tetraspan TM4SF
Function
May play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature sheath.
Biological Process
Biological Process astrocyte development Source:Ensembl
Biological Process axon development Source:Ensembl
Biological Process brain development Source:Ensembl
Biological Process inflammatory response Source:Ensembl
Biological Process microglia development Source:Ensembl
Biological Process myelination Source:Ensembl
Biological Process oligodendrocyte differentiation Source:Ensembl
Cellular Location
Membrane
Topology
Cytoplasmic: 1-13
Helical: 14-34
Extracellular: 35-54
Helical: 55-75
Cytoplasmic: 76-90
Helical: 91-111
Extracellular: 112-188
Helical: 189-209
Cytoplasmic: 210-221
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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