TSPAN2
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq]
Full Name
tetraspanin 2
Function
May play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature sheath.
Biological Process
Biological Process astrocyte development Source:Ensembl
Biological Process axon development Source:Ensembl
Biological Process brain development Source:Ensembl
Biological Process inflammatory response Source:Ensembl
Biological Process microglia development Source:Ensembl
Biological Process myelination Source:Ensembl
Biological Process oligodendrocyte differentiation Source:Ensembl
Biological Process axon development Source:Ensembl
Biological Process brain development Source:Ensembl
Biological Process inflammatory response Source:Ensembl
Biological Process microglia development Source:Ensembl
Biological Process myelination Source:Ensembl
Biological Process oligodendrocyte differentiation Source:Ensembl
Cellular Location
Membrane
Topology
Cytoplasmic: 1-13
Helical: 14-34
Extracellular: 35-54
Helical: 55-75
Cytoplasmic: 76-90
Helical: 91-111
Extracellular: 112-188
Helical: 189-209
Cytoplasmic: 210-221
Helical: 14-34
Extracellular: 35-54
Helical: 55-75
Cytoplasmic: 76-90
Helical: 91-111
Extracellular: 112-188
Helical: 189-209
Cytoplasmic: 210-221
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Anti-TSPAN2 antibodies
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Target: TSPAN2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYJT-5073
Application*: SE, E, WB
Target: TSPAN2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-5072
Application*: F, MC
Target: TSPAN2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-5071
Application*: E, WB
Target: TSPAN2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYJT-5070
Application*: E, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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