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Mouse Anti-TSPY1 Recombinant Antibody (CBYJT-5095) (CBMAB-T4673-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TSPY1 (Testis Specific Protein, Y-Linked 1). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all TSPY1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-5095
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
TSPY1 (NP_003299, 201 a.a. ~ 308 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: IMLFFRSNPY FQNKVITKEY LVNITEYRAS HSTPIEWYPD YEVEAYRRRH HNSSLNFFNW FSDHNFAGSN KIAEILCKDL WRNPLQYYKR MKPPEEGTET SGDSQLLS
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 201-308

Target

Full Name
testis specific protein, Y-linked 1
Introduction
TSPY1 is found only in testicular tissue and may be involved in spermatogenesis. Many functional paralogs and pseudogenes of TSPY1 are present in a cluster in humans, but only a single, nonfunctional orthologous gene is found in mouse.
Entrez Gene ID
7258
UniProt ID
Q01534
Alternative Names
Testis Specific Protein, Y-Linked 1; Cancer/Testis Antigen 78; TSPY; CT78; Testis-Specific Y-Encoded Protein 1; Testis Specific Protein, Y-Linked; PJA923; DYS14
Function
May be involved in sperm differentiation and proliferation.
Biological Process
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process gonadal mesoderm development Source:UniProtKB-KW
Biological Process nucleosome assembly Source:InterPro
Biological Process sex differentiation Source:ProtInc1 Publication
Biological Process spermatogenesis Source:UniProtKB-KW
Cellular Location
Cytoplasm
Nucleus
Predominantly cytoplasmic. Also found in nucleus.
Involvement in disease
TSPY is located in the gonadoblastoma critical region and is preferentially expressed in tumor germ cells of gonadoblastoma specimens. Expression also correlates with testicular seminoma and tumorigenesis of the prostate gland.
PTM
Phosphorylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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