TSPY1

TSPY1 is found only in testicular tissue and may be involved in spermatogenesis. Many functional paralogs and pseudogenes of TSPY1 are present in a cluster in humans, but only a single, nonfunctional orthologous gene is found in mouse.

Full Name

testis specific protein, Y-linked 1

Function

May be involved in sperm differentiation and proliferation.

Biological Process

Biological Process cell differentiation Source:UniProtKB-KW
Biological Process gonadal mesoderm development Source:UniProtKB-KW
Biological Process nucleosome assembly Source:InterPro
Biological Process sex differentiation Source:ProtInc1 Publication
Biological Process spermatogenesis Source:UniProtKB-KW

Cellular Location

Cytoplasm
Nucleus
Predominantly cytoplasmic. Also found in nucleus.

Involvement in disease

TSPY is located in the gonadoblastoma critical region and is preferentially expressed in tumor germ cells of gonadoblastoma specimens. Expression also correlates with testicular seminoma and tumorigenesis of the prostate gland.

PTM

Phosphorylated.

Anti-TSPY1 antibodies

Mouse Anti-TSPY1 Recombinant Antibody (CBYJT-5095) (CBMAB-T4673-YJ)

Datasheet

SDS

Target: TSPY1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJT-5095

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)