Sign in or Register   Sign in or Register
  |  

Mouse Anti-TUBGCP4 Recombinant Antibody (CBFYH-3671) (CBMAB-H4232-FY)

This product is mouse antibody that recognizes TUBGCP4. The antibody CBFYH-3671 can be used for immunoassay techniques such as: WB, IF.
See all TUBGCP4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-3671
Antibody Isotype
IgG2b
Application
WB, IF

Basic Information

Immunogen
Recombinant protein encompassing a sequence within the center region of human GCP4
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TUBGCP4 Gene(Protein Coding)


Tubulin Gamma Complex Associated Protein 4
Introduction
This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
27229
UniProt ID
Q9UGJ1
Alternative Names
Tubulin Gamma Complex Associated Protein 4; Gamma-Ring Complex Protein 76 KDa; GCP-4; GCP4; 76P; Gamma Tubulin Ring Complex Protein (76p Gene); Tubulin, Gamma Complex Associated Protein 4
Function
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Biological Process
Biological Process cytoplasmic microtubule organization Source:GO_Central1 Publication
Biological Process meiotic cell cycle Source:GO_Central1 Publication
Biological Process microtubule nucleation Source:GO_Central1 Publication
Biological Process mitotic cell cycle Source:GO_Central1 Publication
Biological Process protein-containing complex assembly Source:ProtInc1 Publication
Biological Process spindle assembly Source:GO_Central1 Publication
Cellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Involvement in disease
Microcephaly and chorioretinopathy, autosomal recessive, 3 (MCCRP3):
A disorder characterized by congenital microcephaly and chorioretinal dysplasia associated with poor vision and nystagmus. Variable ocular anomalies include microphthalmia, retinal folding, retinal detachment, optic nerve hypoplasia, absence of retinal vessels, round areas of chorioretinal atrophy, and attenuated electroretinogram. Most patients have mild developmental delay and mild learning difficulties.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-TUBGCP4 Recombinant Antibody (CBFYH-3671)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare