Mouse Anti-TUBGCP4 Recombinant Antibody (GT812) (CBMAB-G6678-LY)

Name: Mouse Anti-TUBGCP4 Recombinant Antibody (GT812)
SKU: CBMAB-G6678-LY
Rating: 5 (1 reviews)

See all TUBGCP4 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

GT812

Application

ICC, IF, WB

Immunogen

Recombinant protein fragment contains a sequence corresponding to a region within amino acids 1 and 178 of GCP4

Specificity

Human

Antibody Isotype

IgG2b

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

1 mg/mL

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

TUBGCP4 Gene(Protein Coding)

Tubulin Gamma Complex Associated Protein 4

Introduction

This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]

Entrez Gene ID

27229

UniProt ID

Q9UGJ1

Alternative Names

Tubulin Gamma Complex Associated Protein 4; Gamma-Ring Complex Protein 76 KDa; GCP-4; GCP4; 76P; Gamma Tubulin Ring Complex Protein (76p Gene); Tubulin; Gamma Complex Associated Protein 4;

Function

Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.

Biological Process

Biological Process cytoplasmic microtubule organization Source:GO_Central1 Publication
Biological Process meiotic cell cycle Source:GO_Central1 Publication
Biological Process microtubule nucleation Source:GO_Central1 Publication
Biological Process mitotic cell cycle Source:GO_Central1 Publication
Biological Process protein-containing complex assembly Source:ProtInc1 Publication
Biological Process spindle assembly Source:GO_Central1 Publication

Cellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Involvement in disease

Microcephaly and chorioretinopathy, autosomal recessive, 3 (MCCRP3):
A disorder characterized by congenital microcephaly and chorioretinal dysplasia associated with poor vision and nystagmus. Variable ocular anomalies include microphthalmia, retinal folding, retinal detachment, optic nerve hypoplasia, absence of retinal vessels, round areas of chorioretinal atrophy, and attenuated electroretinogram. Most patients have mild developmental delay and mild learning difficulties.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-TUBGCP4 Recombinant Antibody (GT812)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-TUBGCP4 Recombinant Antibody (CBFYH-3671) (CAT#: CBMAB-H4232-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry