Mouse Anti-TUSC2 Recombinant Antibody (1550CT388.74.12) (CBMAB-T4993-YJ)

Name: Mouse Anti-TUSC2 Recombinant Antibody (1550CT388.74.12)
SKU: CBMAB-T4993-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

1550CT388.74.12

Application

ELISA, WB

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS

Preservative

0.09% Sodium Azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Tumor Suppressor Candidate 2

Introduction

TUSC2 is a highly conserved lung cancer candidate gene.

Entrez Gene ID

11334

UniProt ID

O75896

Alternative Names

Tumor Suppressor Candidate 2; PDGFA-Associated Protein 2; Fusion 1 Protein; Fus-1 Protein; C3orf11; PDAP2

Function

May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.

Biological Process

Biological Process cell cycle Source:UniProtKB-KW
Biological Process cell maturation Source:Ensembl
Biological Process inflammatory response Source:GO_Central1 Publication
Biological Process natural killer cell differentiation Source:Ensembl
Biological Process negative regulation of interleukin-17 production Source:Ensembl
Biological Process neutrophil-mediated killing of gram-negative bacterium Source:Ensembl
Biological Process phagocytosis Source:Ensembl
Biological Process positive regulation of interleukin-10 production Source:Ensembl
Biological Process regulation of mitochondrial membrane potential Source:GO_Central1 Publication
Biological Process regulation of reactive oxygen species metabolic process Source:Ensembl

Cellular Location

Mitochondrion

PTM

Myristoylation is required for tumor suppressor activity.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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