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Mouse Anti-TUSC2 Recombinant Antibody (1550CT388.74.12) (CBMAB-T4993-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1550CT388.74.12
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS
Preservative
0.09% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Tumor Suppressor Candidate 2
Introduction
TUSC2 is a highly conserved lung cancer candidate gene.
Entrez Gene ID
11334
UniProt ID
O75896
Alternative Names
Tumor Suppressor Candidate 2; PDGFA-Associated Protein 2; Fusion 1 Protein; Fus-1 Protein; C3orf11; PDAP2
Function
May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.
Biological Process
Biological Process cell cycle Source:UniProtKB-KW
Biological Process cell maturation Source:Ensembl
Biological Process inflammatory response Source:GO_Central1 Publication
Biological Process natural killer cell differentiation Source:Ensembl
Biological Process negative regulation of interleukin-17 production Source:Ensembl
Biological Process neutrophil-mediated killing of gram-negative bacterium Source:Ensembl
Biological Process phagocytosis Source:Ensembl
Biological Process positive regulation of interleukin-10 production Source:Ensembl
Biological Process regulation of mitochondrial membrane potential Source:GO_Central1 Publication
Biological Process regulation of reactive oxygen species metabolic process Source:Ensembl
Cellular Location
Mitochondrion
PTM
Myristoylation is required for tumor suppressor activity.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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