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Mouse Anti-UBE2Q1 Antibody (6B9) (CBMAB-1715CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
6B9
Antibody Isotype
IgG
Application
ELISA, MA

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
UBE2Q1
Introduction
Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart. Among its related pathways are Protein ubiquitination and Class I MHC mediated antigen processing and presentation. GO annotations related to this gene include ligase activity and acid-amino acid ligase activity. It may be involved in hormonal homeostasis in females and involved in regulation of B4GALT1 cell surface expression, B4GALT1-mediated cell adhesion to laminin and embryoid body formation.
Entrez Gene ID
55585
UniProt ID
Q7Z7E8
Alternative Names
GTAP; NICE5; UBE2Q; NICE-5; PRO3094
Function
Catalyzes the covalent attachment of ubiquitin to other proteins (PubMed:22496338).
May be involved in hormonal homeostasis in females. Involved in regulation of B4GALT1 cell surface expression, B4GALT1-mediated cell adhesion to laminin and embryoid body formation (By similarity).
Biological Process
Biological Process embryo implantation Source:Ensembl
Biological Process fertilization Source:Ensembl
Biological Process mating behavior Source:Ensembl
Biological Process prolactin secretion Source:Ensembl
Biological Process protein polyubiquitination Source:GO_Central1 Publication
Biological Process reproductive system development Source:Ensembl
Biological Process suckling behavior Source:Ensembl
Cellular Location
Nucleus
Cell projection, filopodium
Cytoplasm, cytosol
PTM
Autoubiquitinated in vitro in the presence of NEDD4L.
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For research use only. Not intended for any clinical use.

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