UBE2Q1
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart.
Full Name
UBE2Q1
Function
Catalyzes the covalent attachment of ubiquitin to other proteins (PubMed:22496338).
May be involved in hormonal homeostasis in females. Involved in regulation of B4GALT1 cell surface expression, B4GALT1-mediated cell adhesion to laminin and embryoid body formation (By similarity).
May be involved in hormonal homeostasis in females. Involved in regulation of B4GALT1 cell surface expression, B4GALT1-mediated cell adhesion to laminin and embryoid body formation (By similarity).
Biological Process
Biological Process embryo implantation Source:Ensembl
Biological Process fertilization Source:Ensembl
Biological Process mating behavior Source:Ensembl
Biological Process prolactin secretion Source:Ensembl
Biological Process protein polyubiquitination Source:GO_Central1 Publication
Biological Process reproductive system development Source:Ensembl
Biological Process suckling behavior Source:Ensembl
Biological Process fertilization Source:Ensembl
Biological Process mating behavior Source:Ensembl
Biological Process prolactin secretion Source:Ensembl
Biological Process protein polyubiquitination Source:GO_Central1 Publication
Biological Process reproductive system development Source:Ensembl
Biological Process suckling behavior Source:Ensembl
Cellular Location
Nucleus
Cell projection, filopodium
Cytoplasm, cytosol
Cell projection, filopodium
Cytoplasm, cytosol
PTM
Autoubiquitinated in vitro in the presence of NEDD4L.
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Anti-UBE2Q1 antibodies
+ Filters
Target: UBE2Q1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 13F1
Application*: E, M
Target: UBE2Q1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 6B9
Application*: E, M
Target: UBE2Q1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 2F10
Application*: E, M
Target: UBE2Q1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 20C5
Application*: E, M
Target: UBE2Q1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 16B1
Application*: E, M
Target: UBE2Q1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 10F12
Application*: E, M
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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