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UBE2Q1

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart.

Full Name

UBE2Q1

Function

Catalyzes the covalent attachment of ubiquitin to other proteins (PubMed:22496338).
May be involved in hormonal homeostasis in females. Involved in regulation of B4GALT1 cell surface expression, B4GALT1-mediated cell adhesion to laminin and embryoid body formation (By similarity).

Biological Process

Biological Process embryo implantation Source:Ensembl
Biological Process fertilization Source:Ensembl
Biological Process mating behavior Source:Ensembl
Biological Process prolactin secretion Source:Ensembl
Biological Process protein polyubiquitination Source:GO_Central1 Publication
Biological Process reproductive system development Source:Ensembl
Biological Process suckling behavior Source:Ensembl

Cellular Location

Nucleus
Cell projection, filopodium
Cytoplasm, cytosol

PTM

Autoubiquitinated in vitro in the presence of NEDD4L.

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Anti-UBE2Q1 antibodies

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Mouse Anti-UBE2Q1 Antibody (13F1) (CBMAB-1711CQ)

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Target: UBE2Q1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 13F1

Application*: E, M

Mouse Anti-UBE2Q1 Antibody (6B9) (CBMAB-1715CQ)

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Target: UBE2Q1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 6B9

Application*: E, M

Mouse Anti-UBE2Q1 Antibody (2F10) (CBMAB-1714CQ)

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Target: UBE2Q1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 2F10

Application*: E, M

Mouse Anti-UBE2Q1 Antibody (20C5) (CBMAB-1713CQ)

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Target: UBE2Q1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 20C5

Application*: E, M

Mouse Anti-UBE2Q1 Antibody (16B1) (CBMAB-1712CQ)

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Target: UBE2Q1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 16B1

Application*: E, M

Mouse Anti-UBE2Q1 Antibody (10F12) (CBMAB-1710CQ)

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Target: UBE2Q1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 10F12

Application*: E, M

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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