UBE2Q1

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart.

UBE2Q1

Catalyzes the covalent attachment of ubiquitin to other proteins (PubMed:22496338).
May be involved in hormonal homeostasis in females. Involved in regulation of B4GALT1 cell surface expression, B4GALT1-mediated cell adhesion to laminin and embryoid body formation (By similarity).

Biological Process embryo implantation Source:Ensembl
Biological Process fertilization Source:Ensembl
Biological Process mating behavior Source:Ensembl
Biological Process prolactin secretion Source:Ensembl
Biological Process protein polyubiquitination Source:GO_Central1 Publication
Biological Process reproductive system development Source:Ensembl
Biological Process suckling behavior Source:Ensembl

Nucleus
Cell projection, filopodium
Cytoplasm, cytosol

Autoubiquitinated in vitro in the presence of NEDD4L.