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Mouse Anti-UBR2 Monoclonal Antibody (1D12) (CBMAB-0286-LY)

This product is mouse monoclonal antibody recognizes UBR2 of human. The antibody 1D12 immunoassay techniques such as: IP, ELISA.
Host Species
Mouse
Application
IP, ELISA
Immunogen
Recombinant peptide (Full Length)
Antibody Isotype
IgG2a
Specificity
Human
Clone
1D12
Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants. E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A.
Alternative Name
bA49A4.1; C6orf133; dJ392M17.3; KIAA0349
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-0286-LY
Conjugates
Size
Price $
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Second antibody and isotype control