Sign in or Register   Sign in or Register
  |  

Mouse Anti-UCHL5 Recombinant Antibody (854CT5.5.6) (CBMAB-C4472-CN)

This product is a Mouse antibody that recognizes UCHL5. The antibody 854CT5.5.6 can be used for immunoassay techniques such as: WB.
See all UCHL5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
854CT5.5.6
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Purified His-tagged UCH37 protein
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS
Preservative
0.09% Sodium azide
Concentration
Lot-specific

Target

Full Name
UCHL5
Introduction
Protease that specifically cleaves Lys-48-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.
Entrez Gene ID
51377
UniProt ID
Q9Y5K5
Alternative Names
Ubiquitin C-Terminal Hydrolase L5; Ubiquitin Carboxyl-Terminal Hydrolase L5; Ubiquitin C-Terminal Hydrolase UCH37; Ubiquitin Thioesterase L5; INO80 Complex Subunit R; EC 3.4.19.12; UCH-L5;
Function
Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.
Biological Process
Biological Process chromatin remodeling Source:ComplexPortal1 Publication
Biological Process DNA recombination Source:UniProtKB-KW
Biological Process DNA repair Source:UniProtKB-KW
Biological Process forebrain morphogenesis Source:Ensembl
Biological Process lateral ventricle development Source:Ensembl
Biological Process midbrain development Source:Ensembl
Biological Process negative regulation of proteasomal ubiquitin-dependent protein catabolic process Source:UniProtKB1 Publication
Biological Process positive regulation of DNA repair Source:ComplexPortal
Biological Process positive regulation of DNA-templated transcription Source:ComplexPortal1 Publication
Biological Process positive regulation of smoothened signaling pathway Source:FlyBase1 Publication
Biological Process positive regulation of telomere maintenance in response to DNA damage Source:ComplexPortal
Biological Process protein deubiquitination Source:UniProtKB1 Publication
Biological Process regulation of cell cycle Source:ComplexPortal1 Publication
Biological Process regulation of chromosome organization Source:ComplexPortal1 Publication
Biological Process regulation of DNA repair Source:ComplexPortal
Biological Process regulation of DNA replication Source:ComplexPortal1 Publication
Biological Process regulation of DNA strand elongation Source:ComplexPortal1 Publication
Biological Process regulation of embryonic development Source:ComplexPortal
Biological Process regulation of proteasomal protein catabolic process Source:UniProtKB1 Publication
Biological Process telomere maintenance Source:ComplexPortal
Biological Process ubiquitin-dependent protein catabolic process Source:InterPro
Cellular Location
Cytoplasm
Nucleus
Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-UCHL5 Recombinant Antibody (854CT5.5.6)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare