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Rat Anti-UGGT1 Recombinant Antibody (CBCNC-747) (CBMAB-C4536-CN)

This product is a Rat antibody that recognizes UGGT1. The antibody CBCNC-747 can be used for immunoassay techniques such as: WB.
See all UGGT1 antibodies

Summary

Host Animal
Rat
Specificity
Mouse, Rat
Clone
CBCNC-747
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Synthetic peptide corresponding to amino acids 1505-1519 of Rat UGGT.
Specificity
Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
Serum

Target

Full Name
UDP-Glucose Glycoprotein Glucosyltransferase 1
Introduction
UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]
Entrez Gene ID
Mouse320011
Rat171129
UniProt ID
MouseQ6P5E4
RatQ9JLA3
Alternative Names
UDP-Glucose Glycoprotein Glucosyltransferase 1; UDP-Glucose Ceramide Glucosyltransferase-Like 1; UDP--Glc:Glycoprotein Glucosyltransferase; UGCGL1; HUGT1; UGT1; UDP-Glucose:Glycoprotein Glucosyltransferase 1;
Function
Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
Biological Process
Biological Process 'de novo' post-translational protein folding Source:UniProtKB1 Publication
Biological Process endoplasmic reticulum mannose trimming Source:Reactome
Biological Process ER-associated misfolded protein catabolic process Source:GO_Central1 Publication
Biological Process protein N-linked glycosylation via asparagine Source:GO_Central1 Publication
Cellular Location
Endoplasmic reticulum lumen
Endoplasmic reticulum-Golgi intermediate compartment
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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