Mouse Anti-UNC45A Recombinant Antibody (AbS1) (CBMAB-C4660-CN)

Name: Mouse Anti-UNC45A Recombinant Antibody (AbS1)
SKU: CBMAB-C4660-CN
Rating: 5 (1 reviews)

See all UNC45A antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

AbS1

Application

Immunogen

Recombinant human UNC45

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 50% glycerol

Preservative

0.09% Sodium azide

More Infomation

Target

Full Name

Unc-45 Myosin Chaperone A

Introduction

UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]; Chadli et al., 2006 [PubMed 16478993]).[supplied by OMIM, Mar 2008]

Entrez Gene ID

Human	55898
Mouse	101869
Rat	308759

UniProt ID

Human	Q9H3U1
Mouse	Q99KD5
Rat	Q32PZ3

Alternative Names

Unc-45 Myosin Chaperone A; Smooth Muscle Cell Associated Protein-1; GCUNC-45; UNC-45A; SMAP-1; SMAP1; Smooth Muscle Cell-Associated Protein 1; Unc-45 Homolog A (C. Elegans);

Function

Acts as co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen (By similarity).

Biological Process

Biological Process cell differentiation Source:UniProtKB-KW
Biological Process chaperone-mediated protein folding Source:GO_Central1 Publication
Biological Process muscle organ development Source:UniProtKB-KW

Cellular Location

Cytoplasm
Cytoplasm, perinuclear region
Nucleus
Predominant in the perinuclear region. Little protein in the nucleus.

Involvement in disease

Osteootohepatoenteric syndrome (OOHE):
An autosomal recessive disorder characterized by cholestasis, congenital diarrhea, impaired hearing, and bone fragility. Some patients also display mild developmental delay and intellectual disability.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-UNC45A Recombinant Antibody (AbS1)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-UNC45A Recombinant Antibody (CBYC-P858) (CAT#: CBMAB-P3771-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry