Rabbit Anti-UPK1B Recombinant Antibody (CBCNC-803) (CBMAB-C4704-CN)

Name: Rabbit Anti-UPK1B Recombinant Antibody (CBCNC-803)
SKU: CBMAB-C4704-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

CBCNC-803

Application

Immunogen

Synthetic peptide within Human Uroplakin Ib aa 1-100 (N terminal). The exact sequence is proprietary.

Specificity

Mouse, Rat, Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration

0.472 mg/mL

More Infomation

Target

Full Name

uroplakin 1B

Introduction

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

Entrez Gene ID

Human	7348
Mouse	22268
Rat	303924

UniProt ID

Human	O75841
Mouse	Q9Z2C6
Rat	Q566D0

Alternative Names

Uroplakin 1B; Tetraspanin-20; Uroplakin Ib; Tspan-20; TSPAN20; UPIB;

Function

Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity).

Biological Process

Biological Process epithelial cell differentiation Source:UniProtKB1 Publication
Biological Process response to bacterium Source:Ensembl

Cellular Location

Membrane

Topology

Cytoplasmic: 1-15
Helical: 16-36
Extracellular: 37-60
Helical: 61-81
Cytoplasmic: 82-86
Helical: 87-107
Extracellular: 108-229
Helical: 230-250
Cytoplasmic: 251-260

PTM

N-glycosylated with high-mannose oligosaccharides.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-UPK1B Recombinant Antibody (CBCNC-804) (CAT#: CBMAB-C4705-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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