Rabbit Anti-USP22 Recombinant Antibody (CBXU-032) (CBMAB-U0148-CQ)

Name: Rabbit Anti-USP22 Recombinant Antibody (CBXU-032)
SKU: CBMAB-U0148-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

CBXU-032

Application

WB, IP, FC, ICC

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

ubiquitin specific peptidase 22

Introduction

Entrez Gene ID

23326

UniProt ID

Q9UPT9

Alternative Names

USP3L

Function

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

Biological Process

Biological Process cell cycle Source:UniProtKB-KW
Biological Process chromatin organization Source:UniProtKB-KW
Biological Process embryo development ending in birth or egg hatching Source:UniProtKB1 Publication
Biological Process histone deubiquitination Source:UniProtKB2 Publications
Biological Process histone H3 acetylation Source:ComplexPortal1 Publication
Biological Process histone ubiquitination Source:UniProtKB1 Publication
Biological Process monoubiquitinated histone deubiquitination Source:ComplexPortal1 Publication
Biological Process monoubiquitinated histone H2A deubiquitination Source:ComplexPortal1 Publication
Biological Process positive regulation of DNA-templated transcription Source:UniProtKB1 Publication
Biological Process positive regulation of mitotic cell cycle Source:UniProtKB1 Publication
Biological Process protein deubiquitination Source:UniProtKB1 Publication
Biological Process regulation of DNA repair Source:ComplexPortal2 Publications
Biological Process regulation of RNA splicing Source:ComplexPortal1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:ComplexPortal1 Publication
Biological Process ubiquitin-dependent protein catabolic process Source:InterPro

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-USP22 Recombinant Antibody (CBXU-086) (CAT#: CBMAB-U0188-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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