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Mouse Anti-USP47 (aa 203-302) Recombinant Antibody (CBXU-100) (CBMAB-U0006-CQ)

This product is a mouse antibody that recognizes USP47 (aa 203-302). The antibody CBXU-100 can be used for immunoassay techniques such as: ELISA, ICC, WB.
See all USP47 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXU-100
Antibody Isotype
IgG2a
Application
ELISA, ICC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Preservative
0.09% sodium azide
Purity
>95% as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 203-302

Target

Full Name
ubiquitin specific peptidase 47
Introduction
Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER).
Entrez Gene ID
55031
UniProt ID
Q96K76
Alternative Names
TRFP
Function
Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level.
Biological Process
Biological Process base-excision repair Source:UniProtKB1 Publication
Biological Process cellular response to DNA damage stimulus Source:UniProtKB1 Publication
Biological Process cellular response to UV Source:UniProtKBBy Similarity
Biological Process intrinsic apoptotic signaling pathway in response to DNA damage Source:Ensembl
Biological Process monoubiquitinated protein deubiquitination Source:UniProtKB1 Publication
Biological Process negative regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source:UniProtKB1 Publication
Biological Process negative regulation of DNA-templated transcription Source:UniProtKB1 Publication
Biological Process negative regulation of G2/M transition of mitotic cell cycle Source:UniProtKB1 Publication
Biological Process negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Source:Ensembl
Biological Process positive regulation of canonical Wnt signaling pathway Source:FlyBase1 Publication
Biological Process positive regulation of cell growth Source:UniProtKB1 Publication
Biological Process protein deubiquitination Source:GO_Central1 Publication
Biological Process regulation of protein stability Source:GO_Central1 Publication
Biological Process response to xenobiotic stimulus Source:UniProtKB1 Publication
Biological Process ubiquitin-dependent protein catabolic process Source:InterPro
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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