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Recombinant Mouse Anti-USP6NL Recombinant Antibody (15-B) (CBMAB-XB1211-YC)

Provided herein is a Mouse Recombinant Antibody against USP6 N-Terminal Like. The antibody can be used for immunoassay techniques, such as IF, IP, WB.
See all USP6NL antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
15-B
Application
IF, IP, WB

Basic Information

Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
USP6 N-Terminal Like
Introduction
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
Entrez Gene ID
9712
UniProt ID
Q92738
Alternative Names
USP6 N-Terminal Like; Related To The N-Terminus Of Tre; USP6NL Intronic Transcript 1 (Non-Protein Coding); Related To The N Terminus Of Tre; USP6 N-Terminal-Like Protein; USP6NL-IT1;
Function
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
Biological Process
Biological Process activation of GTPase activity Source:GO_Central1 Publication
Biological Process Golgi organization Source:UniProtKB2 Publications
Biological Process plasma membrane to endosome transport Source:UniProtKB1 Publication
Biological Process positive regulation of GTPase activity Source:UniProtKB1 Publication
Biological Process regulation of Golgi organization Source:UniProtKB1 Publication
Biological Process retrograde transport, plasma membrane to Golgi Source:UniProtKB1 Publication
Biological Process virion assembly Source:UniProtKB1 Publication
Cellular Location
Golgi apparatus
Cytoplasmic vesicle
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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