USP6NL
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
Full Name
USP6 N-Terminal Like
Function
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
Biological Process
Biological Process activation of GTPase activity Source:GO_Central1 Publication
Biological Process Golgi organization Source:UniProtKB2 Publications
Biological Process plasma membrane to endosome transport Source:UniProtKB1 Publication
Biological Process positive regulation of GTPase activity Source:UniProtKB1 Publication
Biological Process regulation of Golgi organization Source:UniProtKB1 Publication
Biological Process retrograde transport, plasma membrane to Golgi Source:UniProtKB1 Publication
Biological Process virion assembly Source:UniProtKB1 Publication
Biological Process Golgi organization Source:UniProtKB2 Publications
Biological Process plasma membrane to endosome transport Source:UniProtKB1 Publication
Biological Process positive regulation of GTPase activity Source:UniProtKB1 Publication
Biological Process regulation of Golgi organization Source:UniProtKB1 Publication
Biological Process retrograde transport, plasma membrane to Golgi Source:UniProtKB1 Publication
Biological Process virion assembly Source:UniProtKB1 Publication
Cellular Location
Golgi apparatus
Cytoplasmic vesicle
Cytoplasmic vesicle
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Anti-USP6NL antibodies
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Target: USP6NL
Host: Mouse
Specificity: Human, Mouse
Clone: 15-6-11
Application*: IF, IP, WB
Target: USP6NL
Host: Mouse
Specificity: Human
Clone: 15-B
Application*: IF, IP, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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