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Mouse Anti-UTY Recombinant Antibody (CBXU-167) (CBMAB-U0010-CQ)

This product is a mouse antibody that recognizes UTY. The antibody CBXU-167 can be used for immunoassay techniques such as: WB, IP, ELISA.
See all UTY antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
CBXU-167
Antibody Isotype
IgG1
Application
WB, IP, ELISA

Basic Information

Specificity
Human, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Ubiquitously Transcribed Tetratricopeptide Repeat Containing, Y-Linked
Introduction
This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. Diseases associated with UTY include Kabuki Syndrome 1. Among its related pathways are Chromatin organization and Transcriptional misregulation in cancer.
Entrez Gene ID
Human7404
Mouse22290
UniProt ID
HumanO14607
MouseP79457
Alternative Names
UTY; ubiquitously transcribed tetratricopeptide repeat gene, Y-linked; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome; histone demethylase UTY; ubiquitous TPR motif protein UTY; ubiquitously transcribed TPR gene on Y chromosome; ubiquitously-transcribed TPR protein on the Y chromosome; ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein; UTY1; DKFZp686L12190
Function
Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity.
Biological Process
Biological Process chromatin organization Source:UniProtKB-KW
Biological Process heart development Source:GO_Central1 Publication
Biological Process histone H3-K27 demethylation Source:GO_Central1 Publication
Biological Process regulation of gene expression Source:GO_Central1 Publication
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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