Mouse Anti-VAX2 Recombinant Antibody (CBYY-1562) (CBMAB-1632-YY)

Name: Mouse Anti-VAX2 Recombinant Antibody (CBYY-1562)
SKU: CBMAB-1632-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYY-1562

Application

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Ventral Anterior HomeoBovinex 1

Introduction

This gene encodes a homeoBovinex protein and is almost exclusively expressed in the ventral portion of the retina during development. In mouse studies, this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development. [provided by RefSeq, Sep 2008]

Entrez Gene ID

25806

UniProt ID

Q9UIW0

Alternative Names

Ventral Anterior HomeoBovinex 2; DRES93;

Function

Transcription factor that may function in dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists including the expression of a truncated TCF7L2 isoform that cannot bind CTNNB1 and acts therefore as a potent dominant-negative Wnt antagonist. Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle (By similarity).
May be a regulator of axial polarization in the retina.

Biological Process

Biological Process axonogenesis Source:Ensembl
Biological Process central nervous system development Source:GO_Central1 Publication
Biological Process dorsal/ventral axis specification Source:Ensembl
Biological Process ectoderm development Source:ProtInc1 Publication
Biological Process embryonic eye morphogenesis Source:Ensembl
Biological Process forebrain development Source:UniProtKB
Biological Process neuron differentiation Source:GO_Central1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process retina development in camera-type eye Source:Ensembl
Biological Process visual perception Source:ProtInc1 Publication
Biological Process Wnt signaling pathway Source:UniProtKB-KW

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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