Sign in or Register
  |  

Mouse Anti-VHL Recombinant Antibody (CBLY2-124) (CBMAB-V0158-LY)

This product is antibody recognizes VHL. The antibody CBLY2-124 immunoassay techniques such as: WB, IP, IF, ELISA.
Host Species
Mouse
Application
WB, IP, IF, ELISA
Immunogen
Amino acids 154-181 at the C-terminus of VHL of mouse origin
Antibody Isotype
IgG
Specificity
Mouse
Clone
CBLY2-124
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Alternative Name
Vhlh; pVHL
Entrez Gene ID
UniProt ID
Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Submit a review Submit a review and you will get a coupon.
0 reviews
Loading...
For Research Use Only. Not For Clinical Use.
Cat CBMAB-V0158-LY
Conjugates
Size
Price $
  ADD TO CART
Request bulk or custom quote
Second antibody and isotype control