Rabbit Anti-VSTM5 Recombinant Antibody (CBYCV-128) (CBMAB-V0084-YC)

Name: Rabbit Anti-VSTM5 Recombinant Antibody (CBYCV-128)
SKU: CBMAB-V0084-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Rabbit

Clone

CBYCV-128

Application

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

V-Set And Transmembrane Domain Containing 5

Introduction

VSTM5 (V-Set And Transmembrane Domain Containing 5) is a protein coding gene. Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. VSTM5 is involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, VSTM5 regulates synapse formation by altering dendritic spine morphology and actin distribution and promotes formation of unstable neuronal spines such as thin and branched types. VSTM5 regulates neuronal morphogenesis and migration during cortical development in the brain.

Entrez Gene ID

Human	387804
Mouse	69137
Rat	500947

UniProt ID

Human	A8MXK1
Mouse	Q9D806
Rat	Q5M7U7

Alternative Names

V-Set And Transmembrane Domain Containing 5; C11orf90; V-Set And Transmembrane Domain-Containing Protein 5; Chromosome 11 Open Reading Frame 90

Function

Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, regulates synapse formation by altering dendritic spine morphology and actin distribution. Promotes formation of unstable neuronal spines such as thin and branched types. Regulates neuronal morphogenesis and migration during cortical development in the brain.

Biological Process

Biological Process filopodium assembly Source:UniProtKB
Biological Process positive regulation of excitatory synapse assembly Source:UniProtKB
Biological Process protein homooligomerization Source:UniProtKB
Biological Process ventral spinal cord development Source:Ensembl

Cellular Location

Cell membrane
Cell projection, dendrite
Cell projection, axon

Topology

Extracellular: 29-147
Helical: 148-168
Cytoplasmic: 169-200

PTM

N-glycosylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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