Mouse Anti-VTI1B Recombinant Antibody (CBYCV-133) (CBMAB-V0097-YC)

Name: Mouse Anti-VTI1B Recombinant Antibody (CBYCV-133)
SKU: CBMAB-V0097-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYCV-133

Application

WB, IF

Immunogen

Mouse Vti1b aa 9-121

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 9-121

More Infomation

Target

Full Name

Vesicle Transport Through Interaction With T-SNAREs 1B

Introduction

Diseases associated with VTI1B include Hypomyelinating Leukodystrophy. Among its related pathways are wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF) and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotationsshow that VTI1B is related to SNARE binding and chloride channel inhibitor activity. An important paralog of this gene is VTI1A.

Entrez Gene ID

Human	10490
Mouse	53612
Rat	100359512

UniProt ID

Human	Q9UEU0
Mouse	O88384
Rat	P58200

Alternative Names

Vesicle Transport Through Interaction With T-SNAREs 1B; Vesicle Transport V-SNARE Protein Vti1-Like 1; Vti1-Rp1; VTI1L; VTI1; VTI2; Vesicle Transport Through Interaction With T-SNAREs Homolog 1B (Yeast)

Function

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.

Biological Process

Biological Process Golgi to vacuole transport Source:GO_Central1 Publication
Biological Process intra-Golgi vesicle-mediated transport Source:GO_Central1 Publication
Biological Process intracellular protein transport Source:InterPro
Biological Process macroautophagy Source:GO_Central1 Publication
Biological Process membrane fusion Source:ProtInc1 Publication
Biological Process regulation of protein localization to plasma membrane Source:UniProtKB1 Publication
Biological Process retrograde transport, endosome to Golgi Source:GO_Central1 Publication
Biological Process vesicle docking involved in exocytosis Source:ProtInc1 Publication
Biological Process vesicle fusion Source:GO_Central1 Publication
Biological Process vesicle fusion with Golgi apparatus Source:GO_Central1 Publication
Biological Process vesicle-mediated transport Source:ProtInc1 Publication

Cellular Location

Early endosome membrane
Late endosome membrane
Lysosome membrane
Cytoplasmic granule
Recycling endosome membrane

Topology

Cytoplasmic: 2-208
Helical: 209-229
Vesicular: 230-232

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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