VTI1B

VTI1B (Vesicle Transport Through Interaction With T-SNAREs 1B) is a Protein Coding gene. Diseases associated with VTI1B include Hypomyelinating Leukodystrophy. Among its related pathways are wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF) and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include SNARE binding and chloride channel inhibitor activity. An important paralog of this gene is VTI1A.

Full Name

Vesicle Transport Through Interaction With T-SNAREs 1B

Function

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.

Biological Process

Biological Process Golgi to vacuole transport Source:GO_Central1 Publication
Biological Process intra-Golgi vesicle-mediated transport Source:GO_Central1 Publication
Biological Process intracellular protein transport Source:InterPro
Biological Process macroautophagy Source:GO_Central1 Publication
Biological Process membrane fusion Source:ProtInc1 Publication
Biological Process regulation of protein localization to plasma membrane Source:UniProtKB1 Publication
Biological Process retrograde transport, endosome to Golgi Source:GO_Central1 Publication
Biological Process vesicle docking involved in exocytosis Source:ProtInc1 Publication
Biological Process vesicle fusion Source:GO_Central1 Publication
Biological Process vesicle fusion with Golgi apparatus Source:GO_Central1 Publication
Biological Process vesicle-mediated transport Source:ProtInc1 Publication

Cellular Location

Early endosome membrane
Late endosome membrane
Lysosome membrane
Cytoplasmic granule
Recycling endosome membrane

Topology

Cytoplasmic: 2-208
Helical: 209-229
Vesicular: 230-232