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Recombinant Mouse Anti-VTN2 Recombinant Antibody (1A5) (CBMAB-XB1221-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Zebrafish
Clone
1A5
Antibody Isotype
IgG1
Application
IF, WB

Basic Information

Immunogen
GST/His-tagged splice variant of Zebrafish IKKγ protein of 154 amino acids fusion protein
Specificity
Human, Zebrafish
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Splice Variant of Zebrafish IKKg Protein
Introduction
NF-κB (nuclear factor kappaB) is a transcription factor that activates numerous target genes important in mediating innate and adaptive immunity in mammals. Activation by external stimuli such as TNF leads to the activation of kinases (IKK1 and IKK2) that phosphorylate inhibitory proteins I-κB and their subsequent degradation. IKK1 and IKK2 form the catalytic subunits of a complex which includes IKKγ, the regulatory component (also known as NEMO). Mutations in NEMO are the cause of the human disorders incontinentia pigmenti and ectodermal dysplasia (ED-AID).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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