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Mouse Anti-VWA1 Recombinant Antibody (10K63) (CBMAB-V0130-YC)

Provided herein is a Mouse monoclonal antibody against Human VWA1. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all VWA1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
10K63
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Immunogen
Purified, NS0-derived, recombinant human WARP (aa 19-445, Accession #Q6PCB0)
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 19-445

Target

Full Name
Von Willebrand Factor A Domain Containing 1
Introduction
VWA1 belongs to the von Willebrand factor A (VWFA) domain superfamily of extracellular matrix proteins and appears to play a role in cartilage structure and function.
Entrez Gene ID
UniProt ID
Alternative Names
Von Willebrand Factor A Domain Containing 1; Von Willebrand Factor A Domain-Containing Protein 1; Von Willebrand Factor A Domain-Related Protein; WARP
Function
Promotes matrix assembly (By similarity).
Involved in the organization of skeletal muscles and in the formation of neuromuscular junctions (Probable).
Biological Process
Biological Process behavioral response to pain Source:Ensembl
Biological Process extracellular matrix organization Source:Ensembl
Cellular Location
Secreted, extracellular space, extracellular matrix, basement membrane
Involvement in disease
Neuropathy, hereditary motor, with myopathic features (HMNMYO):
An autosomal recessive, neuromyopathic disorder that manifests in childhood or adulthood with proximal and distal muscle weakness predominantly of the lower limbs. Affected individuals have difficulty climbing stairs and problems standing on the heels. Most patients have foot deformities, and some may have leg muscle atrophy. Muscle biopsy and electrophysiologic studies are consistent with both a myopathic process and an axonal motor neuropathy.
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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