Mouse Anti-WDR18 Recombinant Antibody (CBYY-1620) (CBMAB-1691-YY)

Name: Mouse Anti-WDR18 Recombinant Antibody (CBYY-1620)
SKU: CBMAB-1691-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYY-1620

Application

WB, ICC

Specificity

Mouse

Antibody Isotype

IgG2b

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Concentration

0.21 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

WD Repeat Domain 18

Introduction

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.

Entrez Gene ID

216156

UniProt ID

Q4VBE8

Alternative Names

WD Repeat Domain 18; Involved In Processing ITS2 3 Homolog (S. Cerevisiae); Involved In Processing ITS2 3 Homolog; WD Repeat-Containing Protein 18; R32184_1; Ipi3;

Function

Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859).
Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (PubMed:21326211).
May play a role during development (By similarity).

Biological Process

Biological Process DNA-templated DNA replication Source:GO_Central1 Publication
Biological Process rRNA processing Source:GO_Central1 Publication

Cellular Location

Nucleus, nucleolus
Nucleus, nucleoplasm
Cytoplasm
Dynein axonemal particle
Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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