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Mouse Anti-WDR18 Recombinant Antibody (CBYY-1620) (CBMAB-1691-YY)

This product is mouse antibody that recognizes WDR18. The antibody CBYY-1620 can be used for immunoassay techniques such as: WB, ICC
See all WDR18 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse
Clone
CBYY-1620
Antibody Isotype
IgG2b
Application
WB, ICC

Basic Information

Specificity
Mouse
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Concentration
0.21 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
WD Repeat Domain 18
Introduction
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.
Entrez Gene ID
216156
UniProt ID
Q4VBE8
Alternative Names
WD Repeat Domain 18; Involved In Processing ITS2 3 Homolog (S. Cerevisiae); Involved In Processing ITS2 3 Homolog; WD Repeat-Containing Protein 18; R32184_1; Ipi3;
Function
Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859).
Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (PubMed:21326211).
May play a role during development (By similarity).
Biological Process
Biological Process DNA-templated DNA replication Source:GO_Central1 Publication
Biological Process rRNA processing Source:GO_Central1 Publication
Cellular Location
Nucleus, nucleolus
Nucleus, nucleoplasm
Cytoplasm
Dynein axonemal particle
Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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