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Mouse Anti-WNT9A Recombinant Antibody (CBWJW-192) (CBMAB-W0079-WJ)

This product is a mouse antibody that recognizes WNT9A. The antibody CBWJW-192 can be used for immunoassay techniques such as: WB, IHC.
See all WNT9A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJW-192
Antibody Isotype
IgG2a
Application
WB, IHC

Basic Information

Immunogen
E. coli-derived recombinant human Wnt-9a, Pro48-Glu92 & Arg231-Phe304.
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Wnt family member 9A
Introduction
WNT9A is a protein-coding gene. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. This gene is a member of the WNT gene family and expressed in gastric cancer cell lines. Among its related pathways are PI3K-Akt signaling pathway and Gastric cancer. An important paralog of this gene is WNT9B.
Entrez Gene ID
7483
UniProt ID
O14904
Alternative Names
WNT14
Function
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal timing of IHH expression during embryonic bone development, normal chondrocyte maturation and for normal bone mineralization during embryonic bone development. Plays a redundant role in maintaining joint integrity.
Biological Process
Biological Process canonical Wnt signaling pathway Source:WormBase1 Publication
Biological Process cell fate commitment Source:GO_Central1 Publication
Biological Process cellular response to retinoic acid Source:UniProtKB
Biological Process cornea development in camera-type eye Source:BHF-UCLBy Similarity
Biological Process embryonic skeletal joint development Source:BHF-UCL
Biological Process iris morphogenesis Source:BHF-UCLBy Similarity
Biological Process negative regulation of cell population proliferation Source:BHF-UCL1 Publication
Biological Process negative regulation of chondrocyte differentiation Source:BHF-UCL
Biological Process neuron differentiation Source:UniProtKB
Cellular Location
Secreted, extracellular space, extracellular matrix
Secreted
PTM
Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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