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Mouse Anti-XAB2 Recombinant Antibody (CBYCX-108) (CBMAB-X0073-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYCX-108
Antibody Isotype
IgG2b
Application
ELISA, IF, IHC-P

Basic Information

Immunogen
Recombinant protein corresponding to aa1-856 of human XAB2.
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
XPA binding protein 2
Introduction
XAB2 is a XPA binding protein 2. XAB2 is involved in pre-mRNA splicing as component of the spliceosome and also involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing.
Entrez Gene ID
56949
UniProt ID
Q9HCS7
Alternative Names
HCNP; HCRN; SYF1; NTC90
Function
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28076346).
Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing (PubMed:10944529, PubMed:17981804).
Biological Process
Biological Process blastocyst development Source:Ensembl
Biological Process cerebral cortex development Source:Ensembl
Biological Process DNA-templated transcription Source:UniProtKB1 Publication
Biological Process generation of catalytic spliceosome for first transesterification step Source:GO_Central1 Publication
Biological Process mRNA splicing, via spliceosome Source:UniProtKB1 Publication
Biological Process transcription-coupled nucleotide-excision repair Source:UniProtKB1 Publication
Cellular Location
Nucleus
Detected in the splicing complex carrying pre-mRNA.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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