Mouse Anti-CHI3L2 Recombinant Antibody (1F8) (CBMAB-Y0073-LY)

Name: Mouse Anti-CHI3L2 Recombinant Antibody (1F8)
SKU: CBMAB-Y0073-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1F8

Application

ELISA, IF, WB

Immunogen

YKT6 (99-198 aa) partial recombinant protein with GST tag. Immunogen sequence: DEFSKQVDRI DWPVGSPATI HYPALDGHLS RYQNPREADP MTKVQAELDE TKIILHNTME SLLERGEKLD DLVSKSEVLG TQSKAFYKTA RKQNSCCAIM

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

YKT6 V-SNARE Homolog

Introduction

This gene product is one of the SNARE recognition molecules implicated in vesicular transport between secretory compartments. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. This protein is highly conserved from yeast to human and can functionally complement the loss of the yeast homolog in the yeast secretory pathway. Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

Entrez Gene ID

10652

UniProt ID

O15498

Function

Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

Biological Process

Biological Process endoplasmic reticulum to Golgi vesicle-mediated transport Source:HGNC-UCL1 Publication
Biological Process protein transport Source:UniProtKB-KW
Biological Process retrograde transport, endosome to Golgi Source:HGNC-UCL1 Publication
Biological Process vesicle docking involved in exocytosis Source:HGNC-UCL1 Publication
Biological Process vesicle targeting Source:HGNC-UCL1 Publication

Cellular Location

Cytoplasm, cytosol
Cytoplasmic vesicle membrane
Golgi apparatus membrane
Probably cycles through vesicles between Golgi and endosomes.

PTM

Palmitoylated; catalyzes its own palmitoylation. Palmitoylation is required for Golgi targeting.
Farnesylation is required for Golgi targeting.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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