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Mouse Anti-YWHAE Recombinant Antibody (8j12) (CBMAB-1241-LY)

This product is antibody recognizes YWHAE. The antibody 8j12 immunoassay techniques such as: ELISA, WB.
Host Species
Mouse
Application
ELISA, WB
Immunogen
Human 14-3-3 epsilon (1-255 aa)
Antibody Isotype
IgG2a, κ
Specificity
Human
Cross Reactivity
Human
Clone
8j12
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity). Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm.
Alternative Name
MDS; HEL2; MDCR; KCIP-1; 14-3-3E
Entrez Gene ID
UniProt ID
Cat CBMAB-1241-LY
Conjugates
Size
Price $
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