Rabbit Anti-ZAN Recombinant Antibody (CBWJZ-013) (CBMAB-Z0021-WJ)

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Basic Information

Host Animal
Rabbit
Clone
CBWJZ-013
Application
WB
Specificity
Mouse, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
More Infomation

Target

Full Name
zonadhesin
Introduction
ZAN (Zonadhesin (Gene/Pseudogene)) is a Protein Coding gene encodes a protein that functions in the species specificity of sperm adhesion to the egg zona pellucida. An allelic polymorphism in this gene results in both functional and frameshifted alleles; the reference genome represents the functional allele. Among its related pathways are Sweet Taste Signaling. An important paralog of this gene is FCGBP.
Entrez Gene ID
Human7455
Mouse22635
UniProt ID
HumanQ9Y493
MouseO88799
Alternative Names
Zonadhesin (Gene/Pseudogene); Zonadhesin
Function
Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.
Biological Process
Biological Process binding of sperm to zona pellucida Source:UniProtKB1 Publication
Biological Process cell-cell adhesion Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Exclusively on the apical region of the sperm head.
Topology
Extracellular: 18-2757
Helical: 2758-2778
Cytoplasmic: 2779-2812
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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