Mouse Anti-ZBTB1 Recombinant Antibody (CBWJZ-036) (CBMAB-Z0073-WJ)
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Basic Information
Target
Represses cAMP-responsive element (CRE)-mediated transcriptional activation (PubMed:21706167).
In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis (PubMed:24657165).
Plays a key role in the transcriptional regulation of T lymphocyte development (By similarity).
Biological Process cellular response to DNA damage stimulus Source:UniProtKB1 Publication
Biological Process cellular response to UV Source:UniProtKB1 Publication
Biological Process chromatin remodeling Source:UniProtKB1 Publication
Biological Process DNA repair Source:UniProtKB1 Publication
Biological Process innate immune response Source:UniProtKB-KW
Biological Process mRNA transcription by RNA polymerase II Source:UniProtKB1 Publication
Biological Process negative regulation of transcription by RNA polymerase II Source:UniProtKB2 Publications
Biological Process positive regulation of natural killer cell differentiation Source:UniProtKB
Biological Process positive regulation of pro-T cell differentiation Source:UniProtKB
Biological Process positive regulation of T cell differentiation Source:UniProtKB
Biological Process positive regulation of T cell mediated immunity Source:UniProtKB
Biological Process protein homooligomerization Source:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process T cell differentiation in thymus Source:Ensembl
Biological Process thymus development Source:UniProtKB
Biological Process translesion synthesis Source:UniProtKB1 Publication
Nucleus, nucleoplasm
Localized in dot-like structures in the nucleus (PubMed:21706167).
Colocalized with SMRT in nuclear bodies (PubMed:20797634).
The sumoylated form is preferentially located in the nucleoplasm outside the nuclear bodies(PubMed:20797634).
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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