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Mouse Anti-ZBTB20 Recombinant Antibody (1F3) (CBMAB-Z0083-WJ)

This product is a mouse antibody that recognizes ZBTB20. The antibody 1F3 can be used for immunoassay techniques such as: WB, IP, IF, IHC-P, ELISA.
See all ZBTB20 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1F3
Antibody Isotype
IgG2a, κ
Application
WB, IP, IF, IHC-P, ELISA

Basic Information

Immunogen
ZBTB20 (AA451-542) partial recombinant protein with GST tag. Immunogen sequence: FLFSLPQPLA GQQTQFVTVS QPGLSTFTAQ LPAPQPLASS AGHSTASGQG EKKPYECTLC NKTFTAKQNY VKHMFVHTGE KPHQCSICWR SF
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid

Target

Full Name
zinc finger and BTB domain containing 20
Introduction
ZBTB20 (Zinc Finger And BTB Domain Containing 20) is a Protein Coding gene which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. Diseases associated with ZBTB20 include Primrose Syndrome and Juvenile Pilocytic Astrocytoma. An important paralog of this gene is ZBTB45.
Entrez Gene ID
26137
UniProt ID
Q9HC78
Alternative Names
HOF; DPZF; PRIMS; ODA-8S; ZNF288
Function
May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses (PubMed:11352661).
Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity).
Biological Process
Biological Process cellular response to glucose stimulus Source:UniProtKB
Biological Process lipid homeostasis Source:UniProtKB
Biological Process negative regulation of gene expression Source:Ensembl
Biological Process positive regulation of glycolytic process Source:UniProtKB
Biological Process positive regulation of interferon-beta production Source:Ensembl
Biological Process positive regulation of interleukin-6 production Source:Ensembl
Biological Process positive regulation of lipid biosynthetic process Source:UniProtKB
Biological Process positive regulation of tumor necrosis factor production Source:Ensembl
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Nucleus
Involvement in disease
Primrose syndrome (PRIMS):
A disease characterized by macrocephaly, intellectual disability, disturbed behavior, dysmorphic facial features, ectopic calcifications, large calcified ear auricles, and progressive muscle wasting.
PTM
Sumoylated with SUMO1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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