Mouse Anti-ZBTB20 Recombinant Antibody (1F3) (CBMAB-Z0083-WJ)

Name: Mouse Anti-ZBTB20 Recombinant Antibody (1F3)
SKU: CBMAB-Z0083-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

1F3

Application

WB, IP, IF, IHC-P, ELISA

Immunogen

ZBTB20 (AA451-542) partial recombinant protein with GST tag. Immunogen sequence: FLFSLPQPLA GQQTQFVTVS QPGLSTFTAQ LPAPQPLASS AGHSTASGQG EKKPYECTLC NKTFTAKQNY VKHMFVHTGE KPHQCSICWR SF

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

More Infomation

Target

Full Name

zinc finger and BTB domain containing 20

Introduction

ZBTB20 (Zinc Finger And BTB Domain Containing 20) is a Protein Coding gene which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. Diseases associated with ZBTB20 include Primrose Syndrome and Juvenile Pilocytic Astrocytoma. An important paralog of this gene is ZBTB45.

Entrez Gene ID

26137

UniProt ID

Q9HC78

Alternative Names

HOF; DPZF; PRIMS; ODA-8S; ZNF288

Function

May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses (PubMed:11352661).
Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity).

Biological Process

Biological Process cellular response to glucose stimulus Source:UniProtKB
Biological Process lipid homeostasis Source:UniProtKB
Biological Process negative regulation of gene expression Source:Ensembl
Biological Process positive regulation of glycolytic process Source:UniProtKB
Biological Process positive regulation of interferon-beta production Source:Ensembl
Biological Process positive regulation of interleukin-6 production Source:Ensembl
Biological Process positive regulation of lipid biosynthetic process Source:UniProtKB
Biological Process positive regulation of tumor necrosis factor production Source:Ensembl
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication

Cellular Location

Nucleus

Involvement in disease

Primrose syndrome (PRIMS):
A disease characterized by macrocephaly, intellectual disability, disturbed behavior, dysmorphic facial features, ectopic calcifications, large calcified ear auricles, and progressive muscle wasting.

PTM

Sumoylated with SUMO1.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Rat Anti-ZBTB20 Recombinant Antibody (4A3) (CAT#: CBMAB-Z0084-WJ)

Isotype control

For research use only. Not intended for any clinical use.

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