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Mouse Anti-ZFPM1 Recombinant Antibody (CBXF-1837) (CBMAB-F3372-CQ)

This product is a mouse antibody that recognizes ZFPM1. The antibody CBXF-1837 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all ZFPM1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBXF-1837
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
zinc finger protein, multitype 1
Introduction
Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2 (By similarity).
Entrez Gene ID
Human161882
Mouse22761
Rat691504
UniProt ID
HumanQ8IX07
MouseO35615
RatD4A168
Alternative Names
ZFPM1; zinc finger protein, FOG family member 1
Function
Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2 (By similarity).
Biological Process
Biological Process atrial septum morphogenesis Source:BHF-UCL
Biological Process atrioventricular valve morphogenesis Source:BHF-UCL
Biological Process cardiac muscle tissue morphogenesis Source:BHF-UCL
Biological Process cell differentiation Source:GO_Central1 Publication
Biological Process definitive erythrocyte differentiation Source:Ensembl
Biological Process embryonic hemopoiesis Source:BHF-UCL
Biological Process erythrocyte differentiation Source:BHF-UCL
Biological Process granulocyte differentiation Source:Ensembl
Biological Process heart development Source:GO_Central1 Publication
Biological Process megakaryocyte development Source:Ensembl
Biological Process megakaryocyte differentiation Source:BHF-UCL
Biological Process mitral valve formation Source:BHF-UCL
Biological Process negative regulation of fat cell differentiation Source:BHF-UCL
Biological Process negative regulation of interleukin-4 production Source:BHF-UCL1 Publication
Biological Process negative regulation of mast cell differentiation Source:BHF-UCL
Biological Process negative regulation of protein binding Source:BHF-UCL
Biological Process negative regulation of transcription by RNA polymerase II Source:BHF-UCL1 Publication
Biological Process outflow tract morphogenesis Source:BHF-UCL
Biological Process platelet formation Source:BHF-UCL1 Publication
Biological Process positive regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process positive regulation of type II interferon production Source:BHF-UCL1 Publication
Biological Process primitive erythrocyte differentiation Source:Ensembl
Biological Process regulation of chemokine production Source:Ensembl
Biological Process regulation of definitive erythrocyte differentiation Source:BHF-UCL1 Publication
Biological Process T-helper cell lineage commitment Source:BHF-UCL1 Publication
Biological Process tricuspid valve formation Source:BHF-UCL
Biological Process ventricular septum morphogenesis Source:BHF-UCL
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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