Rabbit Anti-ZFYVE9 Recombinant Antibody (CBXS-5414) (CBMAB-S2626-CQ)

Name: Rabbit Anti-ZFYVE9 Recombinant Antibody (CBXS-5414)
SKU: CBMAB-S2626-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

CBXS-5414

Application

WB, IP

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Zinc Finger FYVE-Type Containing 9

Introduction

This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants.

Entrez Gene ID

9372

UniProt ID

O95405

Alternative Names

Zinc Finger FYVE-Type Containing 9

Function

Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.

Biological Process

Biological Process endocytosis Source:UniProtKB1 Publication
Biological Process endosomal transport Source:GO_Central1 Publication
Biological Process transforming growth factor beta receptor signaling pathway Source:UniProtKB1 Publication

Cellular Location

Cytoplasm
Early endosome membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Rabbit Anti-ZFYVE9 Recombinant Antibody (CBXS-1523) (CAT#: CBMAB-S4374-CQ)

Rabbit Anti-ZFYVE9 Recombinant Antibody (D5X4F) (CAT#: CBMAB-CP2353-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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