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Rabbit Anti-ZFYVE9 Recombinant Antibody (CBXS-5414) (CBMAB-S2626-CQ)

This product is a rabbit antibody that recognizes ZFYVE9. The antibody CBXS-5414 can be used for immunoassay techniques such as: WB, IP.
See all ZFYVE9 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBXS-5414
Application
WB, IP

Basic Information

Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Zinc Finger FYVE-Type Containing 9
Introduction
This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
9372
UniProt ID
O95405
Alternative Names
Zinc Finger FYVE-Type Containing 9
Function
Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.
Biological Process
Biological Process endocytosis Source:UniProtKB1 Publication
Biological Process endosomal transport Source:GO_Central1 Publication
Biological Process transforming growth factor beta receptor signaling pathway Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
Early endosome membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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