Mouse Anti-ZNF263 Recombinant Antibody (2E9) (CBMAB-A10140-LY)

Name: Mouse Anti-ZNF263 Recombinant Antibody (2E9)
SKU: CBMAB-A10140-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

2E9

Application

WB, ELISA

Immunogen

ZNF263 (NP_005732, 201 a.a. ~ 298 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Zinc Finger Protein 263

Entrez Gene ID

10127

UniProt ID

O14978

Alternative Names

FPM315; ZKSCAN12

Function

Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor (PubMed:32051553).
Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression (PubMed:32051553).
Acts as transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions (PubMed:32277030).

Biological Process

Biological Process negative regulation of transcription by RNA polymerase II Source:UniProtKB1 Publication
Biological Process positive regulation of transcription by RNA polymerase II Source:UniProtKB1 Publication
Biological Process regulation of DNA-templated transcription Source:ProtInc1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication

Cellular Location

Nucleus

PTM

Ubiquitinated, leading to proteasomal degradation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

ZNF263 Matched Antibody Pair (1324) (CAT#: APMAB-1324LY)

ZNF263 Matched Antibody Pair (1325) (CAT#: APMAB-1325LY)

Related Products

Mouse Anti-ZNF263 Recombinant Antibody (1F9) (CAT#: CBMAB-A10141-LY)

Mouse Anti-ZNF263 Recombinant Antibody (2A1) (CAT#: CBMAB-A10142-LY)

Mouse Anti-ZNF263 Recombinant Antibody (2G6) (CAT#: CBMAB-A10143-LY)

ZNF263 Matched Antibody Pair (1325) (CAT#: APMAB-1325LY)

Mouse Anti-ZNF263 Recombinant Antibody (3C9) (CAT#: CBMAB-A10144-LY)

Mouse Anti-ZNF263 Recombinant Antibody (1C11) (CAT#: CBMAB-0868-LY)

Mouse Anti-ZNF263 Recombinant Antibody (6G7) (CAT#: CBMAB-A10145-LY)

ZNF263 Matched Antibody Pair (1324) (CAT#: APMAB-1324LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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