ZNF263
Might play an important role in basic cellular processes as a transcriptional repressor.
Full Name
Zinc Finger Protein 263
Function
Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor (PubMed:32051553).
Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression (PubMed:32051553).
Acts as transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions (PubMed:32277030).
Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression (PubMed:32051553).
Acts as transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions (PubMed:32277030).
Biological Process
Biological Process negative regulation of transcription by RNA polymerase II Source:UniProtKB1 Publication
Biological Process positive regulation of transcription by RNA polymerase II Source:UniProtKB1 Publication
Biological Process regulation of DNA-templated transcription Source:ProtInc1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process positive regulation of transcription by RNA polymerase II Source:UniProtKB1 Publication
Biological Process regulation of DNA-templated transcription Source:ProtInc1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Nucleus
PTM
Ubiquitinated, leading to proteasomal degradation.
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Anti-ZNF263 antibodies
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Target: ZNF263
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 6G7
Application*: WB, E
Target: ZNF263
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3C9
Application*: WB, E
Target: ZNF263
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2G6
Application*: WB, E
Target: ZNF263
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2A1
Application*: WB, E
Target: ZNF263
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1F9
Application*: WB, E
Target: ZNF263
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2E9
Application*: WB, E
Target: ZNF263
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1C11
Application*: IP, M
Target: ZNF263
Specificity: Human
Target: ZNF263
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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