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Mouse Anti-ZNF622 Recombinant Antibody (1C11) (CBMAB-0758-LY)

This product is mouse antibody recognizes ZNF622 of human. The antibody 1C11 immunoassay techniques such as: IP, ELISA.
See all ZNF622 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C11
Antibody Isotype
IgG2a
Application
IP, ELISA

Basic Information

Immunogen
Full length
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
zinc finger protein 622
Introduction
May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development.
Entrez Gene ID
90441
UniProt ID
Q969S3
Alternative Names
MGC17552; MGC2485; ZPR9
Function
Pre-60S-associated cytoplasmic factor involved in the cytoplasmic maturation of the 60S subunit.
Biological Process
Biological Process intrinsic apoptotic signaling pathway in response to oxidative stress Source:UniProtKB1 Publication
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of JNK cascade Source:UniProtKB1 Publication
Biological Process positive regulation of kinase activity Source:UniProtKB1 Publication
Biological Process positive regulation of MAPK cascade Source:UniProtKB1 Publication
Biological Process ribosomal large subunit biogenesis Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
Nucleus
PTM
Phosphorylated by MELK. The phosphorylation may redirect the protein to the nucleus.
Ubiquitinated by HECTD1, leading to its degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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