ZNF622
May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development.
Full Name
zinc finger protein 622
Function
Pre-60S-associated cytoplasmic factor involved in the cytoplasmic maturation of the 60S subunit.
Biological Process
Biological Process intrinsic apoptotic signaling pathway in response to oxidative stress Source:UniProtKB1 Publication
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of JNK cascade Source:UniProtKB1 Publication
Biological Process positive regulation of kinase activity Source:UniProtKB1 Publication
Biological Process positive regulation of MAPK cascade Source:UniProtKB1 Publication
Biological Process ribosomal large subunit biogenesis Source:UniProtKB1 Publication
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of JNK cascade Source:UniProtKB1 Publication
Biological Process positive regulation of kinase activity Source:UniProtKB1 Publication
Biological Process positive regulation of MAPK cascade Source:UniProtKB1 Publication
Biological Process ribosomal large subunit biogenesis Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
Nucleus
Nucleus
PTM
Phosphorylated by MELK. The phosphorylation may redirect the protein to the nucleus.
Ubiquitinated by HECTD1, leading to its degradation.
Ubiquitinated by HECTD1, leading to its degradation.
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Anti-ZNF622 antibodies
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Target: ZNF622
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 4G6
Application*: WB, E
Target: ZNF622
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 3C5
Application*: E, IF, WB
Target: ZNF622
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBWJZ-134
Application*: WB, SE, E, IF
Target: ZNF622
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1C11
Application*: IP, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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