Rat Anti-ZP1 Recombinant Antibody (CBWJZ-277) (CBMAB-Z0714-WJ)

Name: Rat Anti-ZP1 Recombinant Antibody (CBWJZ-277)
SKU: CBMAB-Z0714-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rat

Clone

CBWJZ-277

Application

WB, IP

Specificity

Mouse

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

zona pellucida glycoprotein 1

Introduction

ZP1 (Zona Pellucida Glycoprotein 1) is a Protein Coding gene. Diseases associated with ZP1 include Oocyte Maturation Defect 1 and Female Infertility Due To Zona Pellucida Defect. Among its related pathways are Reproduction. An important paralog of this gene is ZP4.

Entrez Gene ID

22786

UniProt ID

Q62005

Alternative Names

OOMD; OOMD1; HEL163

Function

Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida.

Biological Process

Biological Process binding of sperm to zona pellucida Source:GO_Central1 Publication
Biological Process prevention of polyspermy Source:GO_Central1 Publication

Cellular Location

Processed zona pellucida sperm-binding protein 1
Zona pellucida
Cell membrane

Involvement in disease

Oocyte maturation defect 1 (OOMD1):
An infertility disorder caused by defective oocyte maturation that results in abnormal eggs lacking a zona pellucida. Affected females have normal menstrual cycles and sex hormone levels, no obstruction in the fallopian tubes or abnormalities of the uterus or adnexa.

Topology

Extracellular: 26-601
Helical: 602-622
Cytoplasmic: 623-638

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Rabbit Anti-ZP1 Recombinant Antibody (CBWJZ-276) (CAT#: CBMAB-Z0713-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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