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Mouse Anti-ZSWIM2 Recombinant Antibody (CBWJZ-142) (CBMAB-Z0785-WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJZ-142
Antibody Isotype
IgG2a, κ
Application
S-ELISA, ELISA

Basic Information

Immunogen
ZSWIM2 (AA1-99) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid

Target

Full Name
zinc finger, SWIM-type containing 2
Introduction
ZSWIM2 (Zinc Finger SWIM-Type Containing 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ligase activity and protein self-association.
Entrez Gene ID
151112
UniProt ID
Q8NEG5
Alternative Names
MEX; ZZZ2
Function
E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes.
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process positive regulation of extrinsic apoptotic signaling pathway via death domain receptors Source:Ensembl
Biological Process protein polyubiquitination Source:Ensembl
PTM
Polyubiquitinated. Polyubiquitination is followed by degradation via the proteasome (By similarity).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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