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ZSWIM2

ZSWIM2 (Zinc Finger SWIM-Type Containing 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ligase activity and protein self-association.

Full Name

zinc finger, SWIM-type containing 2

Function

E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes.

Biological Process

Biological Process apoptotic process Source:UniProtKB-KW
Biological Process positive regulation of extrinsic apoptotic signaling pathway via death domain receptors Source:Ensembl
Biological Process protein polyubiquitination Source:Ensembl

PTM

Polyubiquitinated. Polyubiquitination is followed by degradation via the proteasome (By similarity).

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Anti-ZSWIM2 antibodies

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Mouse Anti-ZSWIM2 Recombinant Antibody (2G4) (CBMAB-Z0786-WJ)

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Target: ZSWIM2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2G4

Application*: E

Mouse Anti-ZSWIM2 Recombinant Antibody (CBWJZ-142) (CBMAB-Z0785-WJ)

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Target: ZSWIM2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBWJZ-142

Application*: SE, E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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