ZSWIM2

ZSWIM2 (Zinc Finger SWIM-Type Containing 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ligase activity and protein self-association.

Full Name

zinc finger, SWIM-type containing 2

Function

E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes.

Biological Process

Biological Process apoptotic process Source:UniProtKB-KW
Biological Process positive regulation of extrinsic apoptotic signaling pathway via death domain receptors Source:Ensembl
Biological Process protein polyubiquitination Source:Ensembl

PTM

Polyubiquitinated. Polyubiquitination is followed by degradation via the proteasome (By similarity).

Anti-ZSWIM2 antibodies

Mouse Anti-ZSWIM2 Recombinant Antibody (2G4) (CBMAB-Z0786-WJ)

Datasheet

SDS

Target: ZSWIM2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2G4

Application*: E

Mouse Anti-ZSWIM2 Recombinant Antibody (CBWJZ-142) (CBMAB-Z0785-WJ)

Datasheet

SDS

Target: ZSWIM2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBWJZ-142

Application*: SE, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)